WebDec 1, 2024 · Anti–neutrophil cytoplasm antibody (ANCA)–associated vasculitis (AAV) is a multisystem disease that can present with life-threatening features, including diffuse alveolar hemorrhage (DAH) and rapidly progressive glomerulonephritis (GN). 1 DAH is associated with early mortality in AAV, with 1-year survival varying from 50% to 82%, and … WebJan 9, 2024 · Idiopathic Membranous nephropathy (IMN) is an auto-immune glomerular disease. Recent studies suggest that circulating auto-antibodies against the podocyte …
CYCLOPHOSPHAMIDE injection, for intravenous use - Food …
WebPharmacodynamics. Cyclophosphamide is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in … WebObjective: Glomerulonephritis is a severe manifestation of systemic lupus erythematosus (SLE) that is usually treated with an extended course of intravenous (IV) cyclophosphamide (CYC). Given the side effects of this regimen, we evaluated the efficacy and the toxicity of a course of low-dose IV CYC prescribed as a remission-inducing treatment, followed by … ati sullivan mo
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WebJun 28, 2024 · Rapidly progressive glomerulonephritis (RPGN) is a disease of the kidney characterized clinically by a rapid decrease in the glomerular filtration rate (GFR) … WebAug 19, 2024 · The results of kidney biopsy, combined with clinical manifestation and laboratory findings prompted the diagnosis of rapidly progressing glomerulonephritis (RPGN) in the course of p-ANCA vasculitis. Initial treatment consisted of heamodialyses, remdesivir, plasmaphereses, intravenous immunoglobulins, antibiotics, corticosteroids … WebDec 7, 2024 · Abstract Objectives: To develop a simultaneous population pharmacokinetic model of cyclophosphamide (CY) and 4-hydroxycyclophosphamide (4-OH) in patients with glomerulonephritis. Methods: In total, 23 patients participated in a pharmacokinetic evaluation using dense plasma sampling. fv abbot