Strictosidine synthase-like
WebGene ID: 107790267, updated on 2-Jun-2024. Summary Other designations. protein STRICTOSIDINE SYNTHASE-LIKE 10-like, strictosidine synthase-like protein, strictosidine synthase-like protein WebDespite these differences, comparison of conserved catalytic features of the arylesterase-like and SGL enzymes with the SSs identified similar structural and mechanistic attributes between the hydrolytic reactions catalyzed by the former and the condensation reaction catalyzed by SS.
Strictosidine synthase-like
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WebAug 28, 2024 · Strictosidine was found to be the key biosynthetic precursor of TIA. It was presented in a wide variety of higher plants . This important molecule is generated by … WebThe hairy roots (HR) of Ophiorrhiza pumila produce camptothecin (CPT), a monoterpenoid indole alkaloid used as a precursor in the synthesis of chemotherapeutic drugs. O. pumila HR culture is considered as a promising alternative source of CPT,
WebMay 1, 2006 · Amine substrate specificity. 18 Notably, strictosidine synthase could synthesize alternative heterocyclic derivatives, utilizing both the 3-(2-aminoethyl)-benzofuran (4) and benzothiophene (5) analogs, though at a diminished rate relative to the tryptamine 1 substrate. Although the low activity of the thiophene substrate precluded a quantitative … WebMar 10, 2006 · Strictosidine synthase (STR1; EC 4.3.3.2) ... STR1-like genes (26 to 39% identity to STR1) form a multigene family, which may be divided into different groups, and may perform different functions and are involved in more than one biochemical pathway (Fabbri et al., 2000).
WebOct 20, 2024 · Genome-wide Identification and Expression Analysis of Strictosidine Synthase Gene in Tea Plant Genome-wide Identification and Expression Analysis of … WebJun 6, 2002 · Protein STRICTOSIDINE SYNTHASE-LIKE 12 Gene SSL12 Status UniProtKB reviewed (Swiss-Prot) Organism Arabidopsis thaliana (Mouse-ear cress) Amino acids 335 …
WebFeb 1, 2008 · The gene encoding strictosidine synthase-like protein 11 was most highly expressed in the young seed, followed by the root. ... Strictosidine synthase (STR) is another key Pictet-Spengler reaction ...
WebJan 1, 2008 · Strictosidine synthase, ... (Figure 2), we propose that the newly deprotonated Glu309 (like acetate in the solution reaction) could also catalyze the rate-limiting deprotonation step (Figure 1, step 5; Figure 2). Strictosidine synthase catalyzes iminium formation, which can be rate limiting in solution. The enzyme acts as a scaffold to … take me baby penthouseStrictosidine synthase (EC 4.3.3.2) is an enzyme in alkaloid biosynthesis that catalyses the condensation of tryptamine with secologanin to form strictosidine in a formal Pictet–Spengler reaction: 3-α(S)-strictosidine + H2O = tryptamine + secologanin Since the condensation of tryptamine and secologanin is the first committed step in alkaloid syn… twist off beer bottle caps historyWebJan 13, 2014 · Results. A thorough transcriptome screening revealed that a strictosidine synthase-like (SSL) gene in the root parasitic plant Orobanche aegyptiaca and the shoot parasitic plant Cuscuta australis showed much higher sequence similarities with those in Brassicaceae than with those in their close relatives, suggesting independent gene … take me away to brighter daysWebNational Center for Biotechnology Information twist of fate 意味WebPhylogenetic analysis and functional characterisation of strictosidine synthase-like genes in Arabidopsis thaliana Funct Plant Biol. 2010 Jan;36 (12):1098-1109. doi: … take me away travel way down hereWebDec 3, 2009 · Phylogenetic analysis of strictosidine synthase-like (SSL) proteins reveals four well supported classes of SSLs in Arabidopsis. To determine if Arabidopsis produces active strictosidine synthase, Arabidopsis protein extracts were assayed for enzymatic activity and cDNAs were expressed in Escherichia coli. twist off beer bottleWebJan 13, 2014 · Here, we report that strictosidine synthase - like ( SSL) genes from Brassicaceae were co-opted by the two parasitic plants, O. aegyptiaca and C. australis. Furthermore, these SSL genes belong to a new member of the SSL gene family and were originated by gene duplication uniquely in Brassicaceae. take me away to the funny farm